Journal of Diabetes and Metabolic Disorders 2004. 3(0):57-.

Fargol BOYA, Bagher LARIJANI, Mohammad PAJOUHI, Jamshid LOTFI, Mohammad Mahdi NORAII, Fatemeh BANDARIAN


Background: type II Diabetes mellitus afflict at least 2 million people in Iran. Neuropathy is one of the most common complications of diabetes and lowers the quality of life of diabetic patients. Since neuropathy can lead to ulcer and amputation; we tried to elucidate the factors that change the progression of diabetic neuropathy.

Methods: In this case-control study, 110 diabetic patients were selected from Shariati hospital diabetes clinic. Michigan Neuropathic Diabetic Scoring (MNDS) was used to differentiate cases from controls. The neuropathic status of patients was confirmed with EMG-NCV. Multiple factors were compared between two groups including ACEI consumption, blood pressure, serum lipid level, sex, smoking, method of diabetes control and its quality. 

Results: Statistically significant relations were found between age, gender, quality of diabetes control and duration of disease and neuropathy (P values: 0.04, 0.04, 0.000 and 0.005). No correlations were found between atherosclerotic risk factors (high BP, hyperlipidemia, cigarette smoking) and diabetic neuropathy. 

Conclusion: In this study hyperglycemia was the only modifiable risk factor of diabetic neuropathy. Glycemic control reduces incidence of neuropathy and slows its progression and improves the quality of life in diabetic patients. More attention should be paid to old, male diabetic patients with poor diabetes control for regular foot exam and more practical educations.


Diabetes mellitus, Neuropathy, Michigan score,


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